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Aflibercept biosimilar - HEXAL

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Drug Profile

Aflibercept biosimilar - HEXAL

Alternative Names: Afqlir; Enzeevu; SOK583; SOK583A1

Latest Information Update: 09 Feb 2026

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At a glance

  • Originator HEXAL
  • Developer HEXAL; Sandoz
  • Class Antineoplastics; Eye disorder therapies; Immunoglobulin Fc fragments; Immunoglobulin fragments; Recombinant fusion proteins
  • Mechanism of Action Placenta growth factor inhibitors; Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Wet age-related macular degeneration
  • Registered Branch retinal vein occlusion; Central retinal vein occlusion; Choroidal neovascularisation; Diabetic macular oedema

Most Recent Events

  • 04 Feb 2026 Launched for Wet age-related macular degeneration (In the elderly, In adults) in Canada (Intravitreous)
  • 30 Oct 2025 Registered for Branch retinal vein occlusion (In adults, In the elderly) in Canada (Intravitreous)
  • 30 Oct 2025 Registered for Central retinal vein occlusion (In adults, In the elderly) in Canada (Intravitreous)

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