HB 0025
Alternative Names: HB-0025; Recombinant human anti-PD-L1 monoclonal antibody-VEGFR1 fusion proteinLatest Information Update: 20 Jul 2024
At a glance
- Originator Huabo Biopharm
- Class Antineoplastics; Immunotherapies; Monoclonal antibodies; Recombinant fusion proteins
- Mechanism of Action Antibody-dependent cell cytotoxicity; Cytotoxic T lymphocyte stimulants; Programmed cell death-1 ligand-1 inhibitors; Vascular endothelial growth factors inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Renal cell carcinoma
- Phase I/II Solid tumours
Most Recent Events
- 31 May 2024 HB 0025 is still in phase I trials for Solid tumours (Late-stage disease, Second-line therapy or greater) in USA
- 31 May 2024 Updated efficacy and adverse events data from a phase I trial in Solid tumours presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
- 31 May 2024 Efficacy and adverse events data from a phase II trial in Renal cell carcinoma presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)