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ADR 002

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Drug Profile

ADR 002

Alternative Names: ADR-002; ADR-002K

Latest Information Update: 06 Oct 2025

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At a glance

  • Originator Osaka University Hospital; Rohto Pharmaceutical
  • Class Cardiovascular therapies; Gene therapies; Mesenchymal stem cell therapies; Stem cell therapies
  • Mechanism of Action Cell replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Cardiomyopathies

Most Recent Events

  • 25 Sep 2025 ADR 002 is still in phase I trials for cardiomyopathies in Japan.
  • 25 Sep 2025 Rohto Pharmaceuticals plans a phase II trial for Chronic heart failure in an unknown location in September 2025 (NCT07192211) (jRCT2053250022)
  • 16 Nov 2024 Efficacy and adverse events data from a phase I trial Cardiomyophathies presented at the American Heart Association Scientific Sessions 2024 (AHA-2024)

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