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SENTI 202

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Drug Profile

SENTI 202

Alternative Names: SENTI-202

Latest Information Update: 12 Dec 2025

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At a glance

  • Originator Senti Biosciences
  • Class Antineoplastics; CAR-NK cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; Natural killer cell replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Haematological malignancies
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Haematological malignancies

Most Recent Events

  • 08 Dec 2025 SENTI 202 receives Regenerative Medicine Advanced Therapy (RMAT) status for Acute myeloid leukaemia (Second-line therapy or greater) in USA
  • 08 Dec 2025 Averse event, efficacy, pharmacodynamic and pharmacokinetic data from a phase I trial in Acute myeloid leukemia released by Senti Biosciences
  • 18 Jun 2025 SENTI 202 receives Orphan Drug status for Haematological malignancies (Second-line therapy or greater) in USA

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