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TAA 013

Drug Profile

TAA 013

Alternative Names: Anti-HER2 ADC - TOT Biopharm; TAA013; Trastuzumab antibody drug conjugate - TOT Biopharm

Latest Information Update: 19 Oct 2023

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At a glance

  • Originator TOT Biopharm
  • Class Antineoplastics; Drug conjugates; Immunotoxins; Maytansinoids; Monoclonal antibodies
  • Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Discontinued HER2 positive breast cancer

Most Recent Events

  • 16 Oct 2023 Discontinued - Phase-III for HER2-positive-breast-cancer in China (IV)
  • 01 Feb 2023 Phase-III development in HER2-positive-breast-cancer is ongoing in China (IV) (TOT Biopharma pipeline, February 2023)
  • 08 Dec 2020 Efficacy and adverse events data from a phase I trial in HER2-positive-breast-cancer presented at the 43rd Annual San Antonio Breast Cancer Symposium (SABCS-2020)
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