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Tazbentetol - Spinogenix

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Drug Profile

Tazbentetol - Spinogenix

Alternative Names: SPG-302; Tazbentetol-Spinogenix

Latest Information Update: 25 Dec 2025

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At a glance

  • Originator Spinogenix
  • Class Antidementias; Antiglaucomas; Antineoplastics; Antipsychotics; Benzene derivatives; Benzothiazoles; Ethylene glycols; Neuroprotectants; Small molecules
  • Mechanism of Action Synaptic transmission modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyotrophic lateral sclerosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Alzheimer's disease; Amyotrophic lateral sclerosis; Schizophrenia
  • Preclinical Glaucoma

Most Recent Events

  • 08 Dec 2025 Spinogenix completes phase II clinical trials in Alzheimer's disease in Australia (PO) (NCT06427668)
  • 08 Dec 2025 Updated efficacy, adverse events and pharmacodynamics data from a phase II clinical trial in Alzheimer's disease
  • 01 Dec 2025 The International Nonproprietary Names (INN) Expert Committee of the World Health Organization approves 'tazbentetol' as the non-proprietary name of SPG

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