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Daraxonrasib - REVOLUTION Medicines

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Drug Profile

Daraxonrasib - REVOLUTION Medicines

Alternative Names: RAS(ON) inhibitor- REVOLUTION Medicines; Ras-IN-2; RASMULTI(ON) Inhibitor - REVOLUTION Medicines; RMC-6236

Latest Information Update: 15 Sep 2025

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At a glance

  • Originator REVOLUTION Medicines
  • Developer Kura Oncology; REVOLUTION Medicines
  • Class Amides; Antineoplastics; Cyclopropanes; Heterocyclic compounds with 4 or more rings; Indoles; Ketones; Methyl ethers; Piperazines; Pyridazines; Pyridines; Small molecules; Thiazoles
  • Mechanism of Action Ras protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Adenocarcinoma; Non-small cell lung cancer
  • Phase I/II Pancreatic cancer
  • Phase I Solid tumours
  • No development reported Colorectal cancer

Most Recent Events

  • 10 Sep 2025 Efficacy and adverse event data from a phase III RASolute 302 trial in Adenocarcinoma released by REVOLUTION Medicines
  • 10 Sep 2025 Efficacy and adverse vent data from a clinical trial in Adenocarcinoma released by Revolution Medicines
  • 07 Sep 2025 Chemical structure information added.

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