Drug Profile

Elsunersen - Praxis-Precision-Medicines

Alternative Names: PRAX-222

Latest Information Update: 26 Jun 2026

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At a glance

Originator Praxis Precision Medicines
Class Antiepileptic drugs; Antisense oligonucleotides
Mechanism of Action Gene silencing; SCN2A protein expression inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

Yes - Epilepsy
New Molecular Entity Yes

Highest Development Phases

Phase III Epilepsy

Most Recent Events

22 Jun 2026 Elsunersen - Praxis-Precision-Medicines receives Breakthrough Therapy status for Epilepsy in USA
06 Apr 2026 Efficacy and adverse events data from a phase I/II EMBRAVE trial in Epilepsy released by Praxis Precision Medicines
12 Jan 2026 Praxis-Precision-Medicines announces intention to submit NDA to US FDA for Epilepsy in 2027

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