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LX 2006

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Drug Profile

LX 2006

Alternative Names: AAVrh.10hFXN; LX-2006

Latest Information Update: 13 Oct 2025

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At a glance

  • Originator Weill Cornell Medicine
  • Developer LEXEO Therapeutics
  • Class Cardiovascular therapies; Gene therapies
  • Mechanism of Action Frataxin expression stimulants; Gene transference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Friedreich's ataxia
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Cardiomyopathies

Most Recent Events

  • 07 Oct 2025 LX 2006 receives Orphan Drug status for Friedreich's ataxia in European Union
  • 07 Oct 2025 Updated efficacy data from a phase-I/II trial in Cardiomyopathies released by LEXEO Therapeutics
  • 07 Jul 2025 LX 2006 receives Breakthrough Therapy status for Friedreich's ataxia in USA

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