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Sonesitatug vedotin - Lepu Biopharma

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Drug Profile

Sonesitatug vedotin - Lepu Biopharma

Alternative Names: AZD-0901; CMG 901; Sone-ve

Latest Information Update: 21 Oct 2026

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At a glance

  • Originator KeyMed Biosciences; Miracogen
  • Developer AstraZeneca; KeyMed Biosciences
  • Class Antineoplastics; Auristatins; Drug conjugates; Immunoconjugates; Immunotherapies; Immunotoxins; Monoclonal antibodies
  • Mechanism of Action Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Gastric cancer; Oesophageal cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Adenocarcinoma
  • Phase II Solid tumours

Most Recent Events

  • 28 Sep 2026 AstraZeneca plans a trial for Gastrointestinal cancer (Combination therapy)
  • 28 Sep 2026 AstraZeneca enters R&D agreement with Summit Therapeutics for Gastrointestinal cancer
  • 28 Jul 2026 Sonesitatug Vedotin - Lepu Biopharma receives Orphan Drug status for Gastric cancer in European Union

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