Drug Profile

mRNA 1644

Alternative Names: eOD-GT8 60mer mRNA Vaccine; mRNA-1644

Latest Information Update: 18 Feb 2026

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At a glance

Originator Moderna Therapeutics
Class AIDS vaccines; RNA vaccines
Mechanism of Action Immunostimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

Highest Development Phases

Phase I HIV infections

Most Recent Events

18 Feb 2026 mRNA 1644 is still in phase-I development in HIV-infections(Prevention) in South Africa (Intraperitoneal) (Moderna Therapeutics pipeline, February 2026)
06 Jan 2026 mRNA 1644 is still in phase I trials for HIV-infections (Prevention) in USA (Moderna Therapeutics pipeline, January 2026)
28 Jun 2025 No recent reports of development identified for phase-I development in HIV-infections(Prevention) in South Africa (Intraperitoneal)

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