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GD2 SADA

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Drug Profile

GD2 SADA

Alternative Names: GD2-SADA; two-step radioimmunotherapy - Y-mAbs Therapeutics

Latest Information Update: 06 Oct 2025

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At a glance

  • Originator Massachusetts Institute of Technology; Memorial Sloan-Kettering Cancer Center
  • Developer Y-mAbs Therapeutics
  • Class Antibodies; Antineoplastics; Immunotherapies; Radioisotopes; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Malignant melanoma; Neuroblastoma; Sarcoma; Small cell lung cancer
  • Preclinical Solid tumours

Most Recent Events

  • 28 May 2025 Y mAbs Therapeutics plans to file an amendment to its current IND for Trial 1001 (part 2B) by the end of 2025
  • 28 May 2025 Pharmacokinetics and adverse event data from a phase I trial in Neuroblastoma released by Y mAbs Therapeutics
  • 21 Apr 2025 Y-mAbs Therapeutics plans to file an IND application for Neuroblastoma (In children) in the first half of 2025 (Y-mAbs Therapeutics pipeline, March 2024)

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