Drug Profile

Elegrobart - Viridian Therapeutics

Alternative Names: VRDN 003; ZL-1109

Latest Information Update: 05 Jan 2026

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At a glance

Originator Viridian Therapeutics
Developer Viridian Therapeutics; ZAI Lab
Class Eye disorder therapies; Monoclonal antibodies
Mechanism of Action IGF type 1 receptor antagonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase III Graves ophthalmopathy

Most Recent Events

05 Dec 2025 Phase-III clinical trials in Graves ophthalmopathy in China (SC) (NCT07211776)
14 Oct 2025 ZAI Labs plans phase III trial study in Thyroid eye disease in China in December 2025 (SC, Injection) (NCT07211776)
15 Sep 2025 Viridian Therapeutics completes enrolment in the REVEAL-1 phase III trial for Graves ophthalmopathy (Thyroid Eye Disease) in USA (NCT06625411)

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