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ONM 501

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Drug Profile

ONM 501

Alternative Names: ONM-501

Latest Information Update: 03 Nov 2025

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At a glance

  • Originator University of Texas Southwestern Medical Center
  • Developer OncoNano Medicine
  • Class Antineoplastics; Immunotherapies; Polymers
  • Mechanism of Action STING1 protein stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Lymphoma; Solid tumours

Most Recent Events

  • 27 Oct 2025 Adverse events, pharmacodynamics and efficacy data from a phase I trial in Solid tumours and Lymphoma released by the OncoNano Medicine
  • 22 Oct 2025 Efficacy and adverse events data from a phase I trial in Solid tumors and Lymphoma presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics (AACR-NCI-EORTC-2025)
  • 13 Oct 2023 Phase-I clinical trials in Lymphoma (Inoperable/Unresectable, Monotherapy, Second-line therapy or greater, Late-stage disease, Recurrent) in USA (Intratumoural) (NCT06022029)

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