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VO 659

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Drug Profile

VO 659

Alternative Names: VO 659

Latest Information Update: 01 Mar 2026

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At a glance

  • Originator Vico Therapeutics
  • Class Antisense oligonucleotides
  • Mechanism of Action RNA modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Spinocerebellar ataxias; Huntington's disease
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Huntington's disease; Spinocerebellar ataxias

Most Recent Events

  • 24 Feb 2026 US FDA approves IND application for VO 659 in USA
  • 24 Feb 2026 Efficacy and adverse event data from a phase I/II trial in Huntington's disease released by Vico Therapeutics
  • 24 Feb 2026 Vico Therapeutics plans a clinical trial for VO 659 in USA in 2026

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