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Pembrolizumab/quavonlimab - Merck Sharp & Dohme

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Drug Profile

Pembrolizumab/quavonlimab - Merck Sharp & Dohme

Alternative Names: Coformulation Pembrolizumab/quavonlimab - Merck Sharp & Dohme; MK 1308A; Pembrolizumab+quavonlimab; Quavonlimab+pembrolizumab; Quavonlimab/pembrolizumab - Merck Sharp & Dohme

Latest Information Update: 24 Apr 2024

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At a glance

  • Originator Merck Sharp & Dohme
  • Developer Eisai Inc; Merck Sharp & Dohme
  • Class Antineoplastics; Antivirals; Immunotherapies; Monoclonal antibodies; Tumour-agnostic therapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Cytotoxic T-lymphocyte antigen 4 inhibitors; Programmed cell death 1 receptor agonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Renal cell carcinoma
  • Phase II Colorectal cancer; Liver cancer; Malignant melanoma; Small cell lung cancer; Solid tumours

Most Recent Events

  • 08 Apr 2024 Merck Sharp & Dohme completes the Phase-I/II clinical trials in Solid tumours (Combination therapy, Metastatic disease, Late-stage disease) in USA, Australia, Canada, Chile, France, Greece, Israel, Italy, Japan, New Zealand, Poland, South Korea, Spain, Sweden, South Africa (IV) (NCT03179436)
  • 05 Apr 2024 Efficacy and adverse events data from the phase Ib/II KEYNOTE-B98 trial in Small cell lung cancer presented at the 115th Annual Meeting of the American Association for Cancer Research (AACR-2024)
  • 18 Jan 2024 Adverse events and efficacy data from a phase II KEYSTEP-004 trial in Liver cancer presented at the Gastrointestinal Cancers Symposium 2024 (ASCO-GCS-2024)

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