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Research programme: engineered toxin bodies - Bristol Myers Squibb/Molecular Templates

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Drug Profile

Research programme: engineered toxin bodies - Bristol Myers Squibb/Molecular Templates

Alternative Names: ETBs - Bristol Myers Squibb/Molecular Templates

Latest Information Update: 28 Mar 2025

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At a glance

  • Originator Bristol-Myers Squibb; Molecular Templates
  • Class Antineoplastics; Bacterial toxins; Drug conjugates; Immunoglobulin fragments; Immunotoxins; Recombinant fusion proteins
  • Mechanism of Action Cell death stimulants; Protein synthesis inhibitors; Proto-oncogene protein c-kit expression inhibitors; TROP2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Cancer

Most Recent Events

  • 28 Mar 2025 No recent reports of development identified for research development in Cancer in USA (Parenteral)
  • 01 Apr 2024 Bristol-Myers Squibb plans to terminates its licence for engineered toxin body effective on June 13, 2024
  • 12 Apr 2022 Pharmacodynamics data from a preclinical studies in Cancer presented at the 113th Annual Meeting of the American Association for Cancer Research (AACR-2022)

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