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ALKS 1140

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Drug Profile

ALKS 1140

Alternative Names: ALKS-1140

Latest Information Update: 16 Sep 2022

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At a glance

  • Originator Alkermes plc
  • Class Behavioural disorder therapies; Neuropsychotherapeutics; Small molecules
  • Mechanism of Action HDAC1 protein inhibitors; HDAC2 protein inhibitors; Histone deacetylase and corepressor complex inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Neurodegenerative disorders
  • Preclinical Neurodevelopmental disorders; Psychiatric disorders

Most Recent Events

  • 23 Aug 2022 Alkermes terminates a phase I trial in Neurodegenerative disorders (In volunteers) in Australia (PO) due to sponsor decision (NCT05019105)
  • 03 Mar 2022 Alkermes suspends a phase I trial in Neurodegenerative disorders (In volunteers) in Australia (PO), to obtain additional data prior to recommencing enrollment (NCT05019105)
  • 13 Oct 2021 Phase-I clinical trials in Neurodegenerative disorders (In volunteers) in Australia (PO) in October 2021 (NCT05019105)

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