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Deupsilocin - Cybin

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Drug Profile

Deupsilocin - Cybin

Alternative Names: CYB-003; Deuterated psilocin - Cybin; Deuterated-Psilocin - Cybin; HLP-003

Latest Information Update: 09 Mar 2026

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At a glance

  • Originator Cybin
  • Class Antidepressants; Antipsychotics; Behavioural disorder therapies; Dimethylamines; Drug withdrawal therapies; Ethylamines; Indoles; Organic deuterium compounds; Phenols; Small molecules; Tryptamines
  • Mechanism of Action Serotonin 5-HT2A receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Major depressive disorder
  • Discontinued Alcoholism; Psychiatric disorders

Most Recent Events

  • 09 Mar 2026 Chemical structure information added.
  • 10 Dec 2025 Phase-III clinical trials in Major depressive disorder (Adjunctive treatment) in United Kingdom, Ireland, Greece, Australia (PO) (NCT06793397)
  • 30 Nov 2025 Cybin initiates a phase III EMBRACE trial in Major Depressive Disorder (Adjunctive treatment) in the USA (PO) (NCT06793397)

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