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CBS 001

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Drug Profile

CBS 001

Alternative Names: Anti-LIGHT monoclonal antibody - Centessa Pharmaceuticals; Anti-TNFSF14-monoclonal-antibody - Centessa Pharmaceuticals; CBS-001

Latest Information Update: 05 Oct 2023

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At a glance

  • Originator Capella BioScience
  • Developer Capella BioScience; Centessa Pharmaceuticals
  • Class Anti-inflammatories; Monoclonal antibodies
  • Mechanism of Action Tumour necrosis factor ligand superfamily member 14 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Suspended Idiopathic pulmonary fibrosis; Inflammation

Most Recent Events

  • 22 Aug 2023 Capella Bioscience and Centessa Pharmaceuticals terminate a phase I trial in Inflammation (In volunteers) in United Kingdom (IV), due to portfolio reprioritisation (NCT05323110)
  • 30 Mar 2023 Suspended - Phase-I for Idiopathic pulmonary fibrosis (In volunteers) in United Kingdom (Parenteral)
  • 30 Mar 2023 Suspended - Phase-I for Inflammation (In volunteers) in United Kingdom (IV)

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