Drug Profile

LB 2

Alternative Names: LB 201 - Centessa Pharmaceuticals; LB-2

Latest Information Update: 28 Aug 2025

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At a glance

Originator Lockbody
Class Antineoplastics; Immunotherapies
Mechanism of Action Antibody-dependent cell cytotoxicity; Cytotoxic T lymphocyte stimulants; Programmed cell death-1 ligand-1 inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

28 Aug 2025 No recent reports of development identified for preclinical development in Solid-tumours in USA (Parenteral)
30 Mar 2022 Centessa Pharmaceuticals plans to file IND for Solid tumours in 2023
01 Jul 2021 Preclinical trials in Solid tumours in USA (Parenteral) (Centessa Pharmaceuticals pipeline, July 2021)

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