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TTX MC 138

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Drug Profile

TTX MC 138

Alternative Names: TTX-MC-138

Latest Information Update: 21 Aug 2024

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At a glance

  • Originator TransCode Therapeutics
  • Class Antineoplastics; Antisense oligonucleotides; Immunotherapies
  • Mechanism of Action Cell death stimulants; Gene silencing; MicroRNA inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours
  • Preclinical Colorectal cancer; Glioblastoma; Osteosarcoma; Pancreatic cancer; Small cell lung cancer; Triple negative breast cancer

Most Recent Events

  • 07 Aug 2024 Phase-I/II clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT06260774)
  • 31 May 2024 Pharmacodynamics, pharmacokinetic and adverse event data from a preclinical trial in Cancer presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
  • 31 May 2024 Pharmacokinetic and adverse event data from a phase 0 trial in Solid tumours presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)

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