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Calpurbatug

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Drug Profile

Calpurbatug

Alternative Names: TRL-1068

Latest Information Update: 19 Jun 2026

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At a glance

  • Originator Trellis Bioscience
  • Class Antibacterials; Monoclonal antibodies
  • Mechanism of Action Bacterial biofilm inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Methicillin-resistant Staphylococcus aureus infections; Bacterial endocarditis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Methicillin-resistant Staphylococcus aureus infections
  • Preclinical Bacterial infections

Most Recent Events

  • 12 Jun 2026 Trellis Bioscience plans a phase I trial for Healthy volunteers in USA (Inhalation) (NCT07644195)
  • 08 Apr 2025 Phase-II clinical trials in Methicillin-resistant Staphylococcus aureus infections in USA (IV) (NCT06621251)
  • 23 Oct 2024 TRL 1068 receives Fast Track designation for Bacterial endocarditis [IV,Infusion] in USA, before October 2024

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