Drug Profile

Tilpisertib fosmecarbil - Gilead Sciences

Alternative Names: GS-5290

Latest Information Update: 21 Jan 2025

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At a glance

Originator Gilead Sciences
Class Anti-inflammatories; Phosphorus compounds; Quinolones; Small molecules; Spiro compounds
Mechanism of Action MAP3K8 protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase II Ulcerative colitis

Most Recent Events

21 Jan 2025 Adverse event data from the phase I trial in Inflammatory bowel diseases presented at the 2024 American College of Clinical Pharmacology Annual Meeting (ACCP-2024)
01 Dec 2023 Phase-II clinical trials in Ulcerative colitis (Treatment-experienced) in Canada (PO) (NCT06029972)
15 Sep 2023 Chemical structure information added

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