CLN 619
Alternative Names: Anti-MICA/MICB monoclonal antibody; CLN-619Latest Information Update: 14 Aug 2024
At a glance
- Originator PDI Therapeutics
- Developer Cullinan Therapeutics
- Class Antineoplastics; Immunotherapies; Monoclonal antibodies
- Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Multiple myeloma; Solid tumours
Most Recent Events
- 07 Aug 2024 Phase-I clinical trials in Multiple myeloma (Second-line therapy or greater) in USA (Parenteral) (NCT06381141)
- 31 May 2024 Efficacy and adverse events data from a phase I trial in Solid tumours presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
- 23 May 2024 Updated efficacy and adverse events data from a phase-I trial in Solid tumours released by Cullinan Oncology