Darlifarnib - Kura Oncology
Alternative Names: KO-2806Latest Information Update: 28 Apr 2026
At a glance
- Originator Kura Oncology
- Class Antineoplastics; Small molecules
- Mechanism of Action Farnesyltranstransferase inhibitors
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Adenocarcinoma; Colorectal cancer; Non-small cell lung cancer; Renal cell carcinoma; Solid tumours
Most Recent Events
- 17 Apr 2026 Updated efficacy data from a phase I trial in Renal cell carcinoma released by Kura Oncology
- 12 Jan 2026 Kura Oncology plans the one or more expansion cohorts of KO 2806 and cabozantinib in patients with advanced renal cell carcinoma in the first half of 2026
- 22 Oct 2025 Pharmacodynamics data from a preclinical trial in Cancer presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2025 (AACR-NCI-EORTC-2025)