Drug Profile

Darlifarnib - Kura Oncology

Alternative Names: KO-2806

Latest Information Update: 28 Oct 2025

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At a glance

Originator Kura Oncology
Class Antineoplastics; Small molecules
Mechanism of Action Farnesyltranstransferase inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I Adenocarcinoma; Colorectal cancer; Non-small cell lung cancer; Renal cell carcinoma; Solid tumours

Most Recent Events

18 Oct 2025 Adverse events and efficacy data from a phase I trial in Non-small cell lung cancer, Renal cell carcinoma, Adenocarcinoma released by Kura Oncology
10 Sep 2025 Phase-I clinical trials in Colorectal cancer (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO)
26 Aug 2025 Chemical structure information added.

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