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Darlifarnib - Kura Oncology

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Drug Profile

Darlifarnib - Kura Oncology

Alternative Names: KO-2806

Latest Information Update: 10 Sep 2025

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At a glance

  • Originator Kura Oncology
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Farnesyltranstransferase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Adenocarcinoma; Colorectal cancer; Non-small cell lung cancer; Renal cell carcinoma; Solid tumours

Most Recent Events

  • 10 Sep 2025 Phase-I clinical trials in Colorectal cancer (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO)
  • 26 Aug 2025 Chemical structure information added.
  • 25 Apr 2025 Pharmacodynamics data from a preclinical trial in Renal cell carcinoma presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)

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