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KO 2806

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Drug Profile

KO 2806

Alternative Names: KO-2806

Latest Information Update: 04 Jul 2025

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At a glance

  • Originator Kura Oncology
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Farnesyltranstransferase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Adenocarcinoma; Non-small cell lung cancer; Renal cell carcinoma; Solid tumours
  • Preclinical Colorectal cancer

Most Recent Events

  • 25 Apr 2025 Pharmacodynamics data from a preclinical trial in Renal cell carcinoma presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 26 Feb 2025 Kura Oncology plans the one or more expansion cohorts of KO 2806 and cabozantinib in patients with advanced renal cell carcinoma in the first half of 2025
  • 23 Oct 2024 Preclinical trials in Colorectal cancer in USA (PO), prior to October 2024

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