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CG 001419

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Drug Profile

CG 001419

Alternative Names: CG-001419

Latest Information Update: 17 Dec 2025

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At a glance

  • Originator Cullgen
  • Class Analgesics; Antineoplastics; Small molecules
  • Mechanism of Action TrkA receptor degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours
  • Phase I Pain

Most Recent Events

  • 12 Dec 2025 Adverse events data from a phase I trial in Pain released by Cullgen
  • 12 Dec 2025 Cullgen completes a phase I trial in Pain (In volunteers) in Australia (PO)
  • 12 Dec 2025 Cullgen remains on track to file an IND in early 2026 and, subject to FDA clearance, plans to initiate a Phase II clinical trials in acute pain in the US in the first half of 2026

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