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Axitinib implant - Alcon

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Drug Profile

Axitinib implant - Alcon

Alternative Names: AR-14034; AR-14034 SR

Latest Information Update: 27 Dec 2023

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At a glance

  • Originator Aerie Pharmaceuticals
  • Developer Aerie Pharmaceuticals; Alcon
  • Class Antineoplastics; Benzamides; Eye disorder therapies; Imidazoles; Indazoles; Pyridines; Small molecules
  • Mechanism of Action Angiogenesis inhibitors; Platelet-derived growth factor beta receptor antagonists; Protein tyrosine kinase inhibitors; Proto-oncogene protein c-kit inhibitors; Vascular endothelial growth factor receptor-1 antagonists; Vascular endothelial growth factor receptor-2 antagonists; Vascular endothelial growth factor receptor-3 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Age-related macular degeneration
  • Preclinical Diabetic macular oedema; Wet age-related macular degeneration

Most Recent Events

  • 27 Dec 2023 Chemical structure information added
  • 06 Dec 2023 Phase-I/II clinical trials in Age-related macular degeneration in USA (Intravitreous) (NCT05769153)
  • 17 Mar 2023 Aerie Pharmaceuticals in collaboration with Alcon Research plans a phase I/II NOVA-1 trial in neovascular Age-related macular degeneration in June 2023 (Intravitreal, Implant) (NCT05769153)

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