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LP 118

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Drug Profile

LP 118

Alternative Names: LP-118

Latest Information Update: 16 Jun 2024

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At a glance

  • Originator Newave Pharmaceuticals
  • Developer Guangzhou Lupeng Pharmaceutical; Newave Pharmaceuticals
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Bcl-X protein inhibitors; Proto-oncogene protein c-bcl-2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Acute myeloid leukaemia; B-cell lymphoma; Chronic lymphocytic leukaemia; Haematological malignancies; Multiple myeloma; Precursor cell lymphoblastic leukaemia-lymphoma; Small cell lung cancer; Solid tumours

Most Recent Events

  • 05 Apr 2024 Pharmacodynamics and adverse event data from a preclinical trial in Small cell lung cancer presented at the 115th Annual Meeting of the American Association for Cancer Research (AACR-2024)
  • 09 Dec 2023 Pharmacodynamics data from the preclinical trial in Cancer presented at the 65th American Society of Hematology Annual Meeting and Exposition 2023 (ASH-Hem 2023)
  • 13 Jan 2023 pharmacodynamics data from a preclinical study in Acute myeloid leukemia (AML) presented at the 64th American Society of Hematology Annual Meeting and Exposition (ASH-2023)

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