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Neoantigen specific TCR-T cell therapy - Alaunos Therapeutics

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Drug Profile

Neoantigen specific TCR-T cell therapy - Alaunos Therapeutics

Latest Information Update: 06 Sep 2023

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At a glance

  • Originator ZIOPHARM Oncology
  • Developer Alaunos Therapeutics
  • Class Antineoplastics; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 15 Aug 2023 Alaunos Therapeutics terminates a TCR-T phase I/II library trial in Solid tumours in USA to focus on its hunTR® TCR discovery platform
  • 25 May 2023 Adverse events and efficacy data from a phase I/II trial in in Solid tumours released by Alaunos Therapeutics
  • 28 Jan 2022 Phase-I/II clinical trials in Solid tumours (Second-line therapy or greater, Late-stage disease, Metastatic disease) in USA (Parenteral) (NCT05194735)

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