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HCW 9218

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Drug Profile

HCW 9218

Alternative Names: Bifunctional TGF-β antagonist/IL-15 protein complex - HCW Biologics; HCW-9218

Latest Information Update: 10 Jun 2024

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At a glance

  • Originator HCW Biologics
  • Developer HCW Biologics; University of Minnesota
  • Class Antineoplastics; Hepatoprotectants; Immunotherapies; Interleukins; Recombinant fusion proteins
  • Mechanism of Action Interleukin 15 replacements; Transforming growth factor beta type II receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Ovarian cancer
  • Phase I/II Pancreatic cancer
  • Phase I Solid tumours
  • Research Fibrosis; Liver cancer; Neurodegenerative disorders; Non-alcoholic fatty liver disease
  • Discontinued Lymphoma; Malignant melanoma; Pulmonary fibrosis

Most Recent Events

  • 15 May 2024 HCW Biologics in collaboration with University of Pittsburgh Medical Center plans a phase II trial for Ovarian cancer (Late-stage disease, Metastatic disease, Combination therapy, Neoadjuvant therapy) in the second half of 2024
  • 15 May 2024 HCW Biologics announces intention to submit an Investigational New Drug (IND) application for Autoimmune disorders in the third quarter of 2024
  • 15 May 2024 HCW Biologics plans a clinical trial for an Autoimmune disorders

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