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LTI 05

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Drug Profile

LTI 05

Alternative Names: LTI-05

Latest Information Update: 15 Jul 2025

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At a glance

  • Originator Lung Therapeutics
  • Developer Rein Therapeutics
  • Class Antifibrotics
  • Mechanism of Action Epithelial sodium channel antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cystic fibrosis

Most Recent Events

  • 15 Jul 2025 LTI 05 is still in preclinical trials for Cystic fibrosis in USA (Rein Therapeutics pipeline, July 2025)
  • 10 Jan 2025 Aileron Therapeutics is now called Rein Therapeutics
  • 31 Oct 2023 Lung Therapeutics has been acquired and merged into Aileron Therapeutics

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