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MTK 458

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Drug Profile

MTK 458

Alternative Names: MTK-458

Latest Information Update: 09 Oct 2023

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At a glance

  • Originator Mitokinin
  • Developer AbbVie
  • Class Antidementias; Antiparkinsonians; Small molecules
  • Mechanism of Action Protein-serine-threonine kinase stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Alzheimer's disease; Huntington's disease; Mitochondrial disorders
  • No development reported Parkinson's disease

Most Recent Events

  • 05 Oct 2023 Pharmacodynamics data from preclinical trial in Mitochondrial disorders released by AbbVie
  • 05 Oct 2023 Mitokinin has been acquired and merged into AbbVie
  • 28 Jul 2023 No recent reports of development identified for preclinical development in Parkinson's-disease in USA

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