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Trophoblast antigen 2 tumour activated T-cell engager therapy - Janux Therapeutics/Merck & Co

Drug Profile

Trophoblast antigen 2 tumour activated T-cell engager therapy - Janux Therapeutics/Merck & Co

Alternative Names: TROP2-TRACTr; Trophoblast Antigen 2 Tumour Activated T-Cell Engager therapy

Latest Information Update: 14 Mar 2023

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At a glance

  • Originator Janux Therapeutics
  • Developer Janux Therapeutics; Merck & Co
  • Class Antineoplastics; Immunoglobulin fragments; Immunotherapies; Peptides; Recombinant fusion proteins
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 10 Mar 2023 Janux Therapeutics announces intention to select a development candidate for its Trophoblast antigen 2 tumour activated T-cell engager therapy in 2023
  • 09 Nov 2021 Janux Therapeutics intends to submit IND application in 2023
  • 21 Apr 2021 Janux Therapeutics plans a clinical trial of TROP2 TRACTr for Solid tumours
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