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SHR 1905

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Drug Profile

SHR 1905

Alternative Names: AIO-001; GSK-5784283; SHR-1905

Latest Information Update: 29 Aug 2025

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At a glance

  • Originator Jiangsu Hengrui Medicine Co.
  • Developer Atridia; GSK; Jiangsu Hengrui Medicine Co.; Shanghai Hengrui Pharmaceutical
  • Class Anti-inflammatories; Antiasthmatics; Monoclonal antibodies
  • Mechanism of Action Thymic stromal lymphopoietin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Asthma; Rhinosinusitis
  • Phase I Chronic obstructive pulmonary disease

Most Recent Events

  • 20 Aug 2025 Guangdong Hengrui Pharmaceutical plans a phase III trial for Rhinosinusitis with Nasal polyps (Treatment-experienced) in China (Parenteral, Injection) in August 2025 (NCT07132827)
  • 01 Aug 2025 Guangdong Hengrui Pharmaceutical plans phase-III trial for Asthma (Treatment-experienced) in China (Parenteral, injection) (NCT07098403)
  • 04 Mar 2025 Phase-II clinical trials in Asthma (Treatment-experienced) in USA (SC) (NCT06748053) (EudraCT2024-518321-15)

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