Drug Profile

E 602

Alternative Names: Bi-Sialidase; E-602; HLX-79

Latest Information Update: 16 Apr 2025

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At a glance

Originator Palleon Pharmaceuticals
Developer Palleon Pharmaceuticals; Shanghai Henlius Biotech
Class Antineoplastics; Enzymes; Immunoglobulin Fc fragments; Recombinant fusion proteins
Mechanism of Action Neuraminidase replacements

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I/II Solid tumours
Preclinical Autoimmune disorders

Most Recent Events

02 Apr 2025 Preclinical trials in Autoimmune disorders in USA (IV) before April 2025
02 Apr 2025 Pharmacodynamics data from a preclinical trial in Autoimmune disorders released by Palleon Pharmaceuticals
25 Mar 2025 NMPA approves IND application for HLX 79 in Glomerulonephritis

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