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JANX 007

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Drug Profile

JANX 007

Alternative Names: JANX-007; Prostate specific membrane antigen tumour activated T-cell engager therapy - Janux Therapeutics/Merck & Co; PSMA TRACTr - Janux Therapeutics/Merck & Co

Latest Information Update: 13 Aug 2025

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At a glance

  • Originator Janux Therapeutics
  • Class Antineoplastics; Immunoglobulin fragments; Immunotherapies; Peptides; Recombinant fusion proteins
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Prostate cancer

Most Recent Events

  • 13 Aug 2025 Clinical trials in Prostate cancer (Parenteral)
  • 24 Jul 2025 Janux Therapeutics plans a clinical trial for Prostate cancer (Hormone refractory, Combination therapy) (IV) in the second half of 2026
  • 08 May 2025 Janux Therapeutics plans a phase Ib expansion trial for Prostate cancer (Inoperable/unresectable, Metastatic disease, Combination therapy) in in 2025

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