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JANX 008

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Drug Profile

JANX 008

Alternative Names: EGFR TRACTr - Janux Therapeutics/Merck & Co; EGFR-TRACTr; Epidermal growth factor receptor tumour activated T-cell engager therapy - Janux Therapeutics/Merck & Co; JANX-008

Latest Information Update: 05 May 2026

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At a glance

  • Originator Janux Therapeutics
  • Class Antineoplastics; Immunoglobulin fragments; Immunotherapies; Peptides; Recombinant fusion proteins
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Solid tumours

Most Recent Events

  • 05 May 2026 Discontinued - Phase-I for Solid tumours (Late-stage disease, Metastatic disease) in USA (IV)
  • 28 Apr 2026 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Metastatic disease) in USA (IV)
  • 10 Feb 2026 Janux Therapeutics has patent protection for JANX 008 in multiple countries before February 2026

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