Human epidermal growth factor receptor 2 tumour activated T-cell engager therapy - Janux Therapeutics/Merck & Co
Alternative Names: HER2 TRACTr - Janux Therapeutics/Merck & Co; HER2-TRACTrLatest Information Update: 28 Apr 2025
At a glance
- Originator Janux Therapeutics
- Developer Janux Therapeutics; Merck & Co
- Class Antineoplastics; Immunoglobulin fragments; Immunotherapies; Peptides; Recombinant fusion proteins
- Mechanism of Action Immunologic cytotoxicity; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- No development reported Solid tumours
Most Recent Events
- 28 Apr 2025 No recent reports of development identified for preclinical development in Solid-tumours in USA (Parenteral)
- 16 Mar 2021 Preclinical trials in Solid tumours in USA (Parenteral) prior to March 2021 (Janux Therapeutics pipeline, March 2021)
- 18 Dec 2020 Merck & Co in-licenses products and intellectual property of Tumor Activated T Cell Engager (TRACTr) technology from Janux Therapeutics