Drug Profile

Research programme: SPL 029 series - Helus Pharma

Alternative Names: Oral DMT series - Helus Pharma; SPL-029 series; SPL029

Latest Information Update: 24 Apr 2026

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At a glance

Originator Small Pharma
Developer Helus Pharma
Class Dimethylamines; Neuropsychotherapeutics; Organic deuterium compounds; Small molecules; Tryptamines
Mechanism of Action Serotonin 5-HT2A receptor agonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

28 Apr 2025 No recent reports of development identified for preclinical development in Mental-disorders in United Kingdom (PO)
12 Feb 2024 9409493: Patent information added, HE added
25 Oct 2023 Cybin has patent protection for Deuterated compounds in USA (US1 177 306 2B2)

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