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Micvotabart pelidotin - Pyxis Oncology

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Drug Profile

Micvotabart pelidotin - Pyxis Oncology

Alternative Names: anti-EDB; MICVO; PYX-201

Latest Information Update: 16 Sep 2026

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At a glance

  • Originator Pfizer
  • Developer Merck & Co; Pyxis Oncology
  • Class Antineoplastics; Auristatins; Drug conjugates; Immunotoxins; Monoclonal antibodies
  • Mechanism of Action Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Solid tumours; Squamous cell cancer

Most Recent Events

  • 09 Sep 2026 Pyxis Oncology plans an end of phase 2 meeting with the US FDA to align on dose selection in the first quarter of 2027
  • 09 Sep 2026 Efficacy and adverse events data form phase I clinical trials in Solid tumours released by Pyxis Oncology
  • 09 Sep 2026 Pyxis Oncology plans phase III Headliner™ trial in Squamous cell cancer (Monotherapy, Second-line therapy and greater, Late-stage disease) in mid of 2027 (IV, Infusion)

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