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Etakafusp alfa - Asher Biotherapeutics

Drug Profile

Etakafusp alfa - Asher Biotherapeutics

Alternative Names: AB-248

Latest Information Update: 16 Jul 2025

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At a glance

  • Originator Asher Biotherapeutics
  • Developer Asher Biotherapeutics; AstraZeneca
  • Class Anti-infectives; Antineoplastics; Immunotherapies; Interleukins; Recombinant fusion proteins
  • Mechanism of Action CD8 positive T lymphocyte stimulants; Interleukin 2 replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Non-small cell lung cancer
  • Phase I Solid tumours

Most Recent Events

  • 16 Jul 2025 Amgen plans a phase I DeLLphi-311 trial for Small cell lung cancer (Combination therapy, Metastatic disease) (IV, Infusion) in July 2025 (NCT07037758)
  • 07 Jul 2025 Phase-I/II clinical trials in Non-small cell lung cancer (Late-stage disease, Metastatic disease, Combination therapy) in Moldova (IV) (NCT06996782)
  • 23 May 2025 AstraZeneca plans the phase I/II ALTAIR trial in Non-small Cell Lung Cancer (Late-stage disease, Metastatic disease) in Belgium, Brazil, China, France, Georgia, South Korea, Malaysia, Moldova, Netherlands, Peru, Poland, Serbia, Spain, Taiwan, Thailand, Turkey and the US (IV) (NCT06996782)

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