Etakafusp alfa - Asher Biotherapeutics
Alternative Names: AB-248Latest Information Update: 16 Jul 2025
At a glance
- Originator Asher Biotherapeutics
- Developer Asher Biotherapeutics; AstraZeneca
- Class Anti-infectives; Antineoplastics; Immunotherapies; Interleukins; Recombinant fusion proteins
- Mechanism of Action CD8 positive T lymphocyte stimulants; Interleukin 2 replacements
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I/II Non-small cell lung cancer
- Phase I Solid tumours
Most Recent Events
- 16 Jul 2025 Amgen plans a phase I DeLLphi-311 trial for Small cell lung cancer (Combination therapy, Metastatic disease) (IV, Infusion) in July 2025 (NCT07037758)
- 07 Jul 2025 Phase-I/II clinical trials in Non-small cell lung cancer (Late-stage disease, Metastatic disease, Combination therapy) in Moldova (IV) (NCT06996782)
- 23 May 2025 AstraZeneca plans the phase I/II ALTAIR trial in Non-small Cell Lung Cancer (Late-stage disease, Metastatic disease) in Belgium, Brazil, China, France, Georgia, South Korea, Malaysia, Moldova, Netherlands, Peru, Poland, Serbia, Spain, Taiwan, Thailand, Turkey and the US (IV) (NCT06996782)