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Etakafusp alfa - Asher Biotherapeutics

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Drug Profile

Etakafusp alfa - Asher Biotherapeutics

Alternative Names: AB-248

Latest Information Update: 06 Oct 2025

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At a glance

  • Originator Asher Biotherapeutics
  • Class Anti-infectives; Antineoplastics; Immunotherapies; Interleukins; Recombinant fusion proteins
  • Mechanism of Action CD8 positive T lymphocyte stimulants; Interleukin 2 replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Small cell lung cancer; Solid tumours

Most Recent Events

  • 06 Oct 2025 AstraZeneca plans a phase Ib/II ALTAIR trial for Non-small cell lung cancer (Metastatic disease, Late-stage disease, Combination therapy) in USA, Belgium, Brazil, China, France, Georgia, Italy, Japan, Malaysia, Moldova, Netherlands, Peru, Poland, Serbia, South Korea, Spain, Taiwan, Thailand and Turkey (IV), in October 2025 (NCT06996782)
  • 16 Sep 2025 Phase-I clinical trials in Small cell lung cancer (Combination therapy, Second-line therapy or greater, Recurrent, Late-stage disease) in USA, Turkey (IV) (NCT07037758)
  • 16 Jul 2025 Amgen plans a phase I DeLLphi-311 trial for Small cell lung cancer (Combination therapy, Metastatic disease) (IV, Infusion) in July 2025 (NCT07037758)

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