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SAR 445419

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Drug Profile

SAR 445419

Alternative Names: KDS-1001; SAR-445419

Latest Information Update: 28 Apr 2025

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At a glance

  • Originator Kiadis Pharma
  • Developer Kiadis Pharma; Sanofi; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Gene therapies; Immunotherapies; Natural killer cell therapies
  • Mechanism of Action Immunologic cytotoxicity; Natural killer cell replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Chronic myeloid leukaemia; Myelodysplastic syndromes
  • Discontinued Acute myeloid leukaemia

Most Recent Events

  • 28 Apr 2025 No recent reports of development identified for preclinical development in Chronic-myeloid-leukaemia in Netherlands (Parenteral, Infusion)
  • 31 Dec 2024 Discontinued - Phase-I for Acute myeloid leukaemia (Second-line therapy or greater) in USA (IV) before December 2024
  • 31 Dec 2024 Discontinued - Phase-I for Acute myeloid leukaemia in France (Parenteral), before December 2024

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