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Research programme: glycogen synthase 1 inhibitors - Maze Therapeutics

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Drug Profile

Research programme: glycogen synthase 1 inhibitors - Maze Therapeutics

Alternative Names: Glycogen synthetase 1 therapeutics - Maze Therapeutics; GYS1 Program - Maze Therapeutics

Latest Information Update: 29 Apr 2021

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At a glance

  • Originator Maze Therapeutics
  • Class Small molecules
  • Mechanism of Action Glucosyltransferase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Glycogen storage disease type II

Most Recent Events

  • 26 Mar 2021 Maze Therapeutics plans to initiate clinical trials for Glycogen storage disease type II, in the US, in the first half of 2022
  • 24 Mar 2021 Preclinical trials in Glycogen storage disease type II in USA (PO), prior to March 2021
  • 24 Mar 2021 Maze Therapeutics announces intention to submit IND to US FDA for Glycogen storage disease type II
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