APVO 442
Alternative Names: APVO 442Latest Information Update: 06 Nov 2025
At a glance
- Originator Aptevo Therapeutics
- Class Antineoplastics; Bispecific antibodies; Immunotherapies
- Mechanism of Action T lymphocyte stimulants
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Preclinical Prostate cancer
Most Recent Events
- 24 Oct 2025 Preclinical development in Prostate cancer is still ongoing in USA (Aptevo Therapeutics pipeline, October 2025)
- 28 May 2025 No recent reports of development identified for preclinical development in Prostate-cancer in USA (Parenteral)
- 21 Apr 2023 Aptevo Therapeutics plans a IND enabling studies for Prostrate Cancer