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Drug Profile


Alternative Names: Magnetic nanocarrier-conjugated siRNA against PDL1 - TransCode Therapeutics; Magnetic nanocarrier-conjugated small interfering RNA against programmed death ligand 1 - TransCode Therapeutics; TTX-siPDL1

Latest Information Update: 15 Nov 2022

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At a glance

  • Originator TransCode Therapeutics
  • Class Antineoplastics; Small interfering RNA
  • Mechanism of Action B7-H1 antigen expression inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Pancreatic cancer; Solid tumours

Most Recent Events

  • 09 Nov 2022 Pharmacodynamics data from a preclinical trial in Pancreatic cancer released by TransCode Therapeutics
  • 11 Aug 2022 Preclinical trials in Pancreatic cancer in USA (Parenteral) (Transcode therapeutics pipeline, August 2022)
  • 14 Jun 2022 TTX siPDL1 receives Orphan Drug status for Pancreatic cancer in USA
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