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Research programme: kt 3000 HDAC and PARP inhibitors - Rakovina Therapeutics

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Drug Profile

Research programme: kt 3000 HDAC and PARP inhibitors - Rakovina Therapeutics

Alternative Names: kt 3000 dual action DNA Damage Response inhibitors - Rakovina Therapeutics; kt-3000; kt-3000 series

Latest Information Update: 28 May 2025

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At a glance

  • Originator Rakovina Therapeutics
  • Developer Rakovina Therapeutics; University of British Columbia
  • Class Antineoplastics; Small molecules
  • Mechanism of Action DNA repair inhibitors; Histone deacetylase inhibitors; Poly(ADP-ribose) polymerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Ewing's sarcoma
  • No development reported Cancer

Most Recent Events

  • 28 May 2025 No recent reports of development identified for preclinical development in Cancer in Canada
  • 28 Nov 2023 Rakovina Therapeutics plans to initiate clinical trials for Ewing's sarcoma, in 2024
  • 11 Oct 2023 Pharmacodynamics data from a preclinical trial in Cancer presented at the International Conference on Molecular Targets and Cancer Therapeutics 2023 (AACR-NCI-EORTC-2023)

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