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Research programme: kt 4000 DNA damage response inhibitors - Rakovina Therapeutics

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Drug Profile

Research programme: kt 4000 DNA damage response inhibitors - Rakovina Therapeutics

Alternative Names: kt 4000 - DNA damaging DDR inhibitors - Rakovina Therapeutics; kt 4000 series; kt-4000

Latest Information Update: 28 May 2025

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At a glance

  • Originator Rakovina Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Alkylating agents; DNA methylation modulators; DNA repair inhibitors; Poly(ADP-ribose) polymerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Cancer

Most Recent Events

  • 28 May 2025 No recent reports of development identified for preclinical development in Cancer in Canada
  • 12 Apr 2022 Pharmacodynamics data from preclinical studies in Cancer presented at the American Association of Cancer Research (AACR) annual general meeting
  • 26 Aug 2021 Rakovina Therapeutics announces intention to file investigational new drug application for kt 4000 series in Cancer

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