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TCB 008

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Drug Profile

TCB 008

Alternative Names: Gamma delta T cell lymphocyte - TC Biopharm; TCB-008; unmodified expanded gamma delta T cell Lymphocytes

Latest Information Update: 23 May 2024

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At a glance

  • Originator TC BioPharm
  • Developer Queen Mary University of London; TC BioPharm
  • Class Antineoplastics; Immunotherapies; T lymphocyte cell therapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Acute myeloid leukaemia
  • Preclinical COVID 2019 infections; Mucositis

Most Recent Events

  • 15 May 2024 TC BioPharm plans a Compassionate Use Program for TCB 008 in UK
  • 22 Feb 2024 TC Biopharma plans to file an additional IND for phase Ib trial for Acute myeloid leukemia (second-line therapy or greater) in USA (IV)in the early 2024
  • 22 Feb 2024 Medicines and Healthcare Products Regulatory Agency accepts amendment to the Clinical Trial Authorization for TCB 008 for Acute myeloid leukemia for review
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